ACHIEVING OPTIMAL JOINT HEALTH: INSIGHTS INTO FLEXIBLE SUPPLEMENT'S EFFICACY

In our quest for optimal joint health and increased flexibility, it's vital to understand that a single solution is rarely the answer. True joint health comes from a comprehensive approach that includes proper nutrition, regular physical activity, and the targeted use of supplements. FLEXIBLE, a meticulously formulated collagen supplement, can be a crucial ally of this holistic strategy. It combines four premium ingredients known for their effectiveness in promoting joint health and flexibility while reducing pain, stiffness, and discomfort.

At LEMAlab, we recognise the complexity of joint health and flexibility. We aim to guide individuals in avoiding injuries resulting from both physical activity and the natural ageing process through proactive prevention measures. Our commitment extends to supporting you in maintaining a youthful, functional and healthy physique by incorporating specific lifestyle choices and leveraging the principles of biohacking.

WHY FLEXIBLE WORKS: IN-DEPTH LOOK AT ITS INGREDIENTS

1. Grass-Fed Premium Quality Bovine Collagen Peptides:

• Joint Health: Collagen is a major component of cartilage, the tissue cushioning joints. This supplement replenishes collagen, easing joint movement and reducing stiffness [9].
• Tendon and Ligament Support: By strengthening and enhancing the quality of connective tissue, it improves flexibility and lowers injury risks during physical activities [5].
• Muscle Health: Collagen underpins muscle elasticity and recovery, vital for physical activities and reducing soreness post-exercise [5].• Bone Health: Collagen contributes to the density and strength of bones. Adequate collagen intake is essential for maintaining bone strength, particularly as we age, helping to support overall joint function [3,8].

2. Glucosamine:

• Cartilage Formation and Maintenance: A natural compound in the body, glucosamine is vital for cartilage health, providing cushioning to joints [11].
• Collagen Production: Glucosamine plays a role in collagen formation, essential for the structural integrity of joint tissue [13].
• Anti-Inflammatory and Lubricating Properties: Its potential anti-inflammatory effects and role in maintaining joint lubrication contribute to smoother joint movement and flexibility [10].

3. Methylsulfonylmethane (MSM):

• Sulfur Source for Collagen Synthesis: MSM is a crucial component for synthesising collagen, integral to joint and connective tissue health [4].
• Anti-Inflammatory and Antioxidant Effects: Its anti-inflammatory and antioxidant properties support joint function and combat oxidative stress [2].
• Joint Lubrication: MSM contributes to the production of synovial fluid, which is essential for reducing friction and enhancing joint movement [6].

4. Bromelain:

• Anti-Inflammatory and Analgesic Effects: Extracted from pineapples, bromelain is known for its anti-inflammatory properties, reducing joint pain and stiffness.
• Supporting Tissue Repair: Its proteolytic activity aids in breaking down damaged proteins in the joints, facilitating repair and regeneration.
• Digestive and Swelling Reduction Benefits: Beyond joint health, bromelain supports digestion and may reduce swelling associated with joint issues [7].

THE SYNERGY FOR OPTIMAL JOINT HEALTH

The combined effects of these ingredients in FLEXIBLE create a collaborative impact. Collagen peptides, glucosamine sulphate, MSM, and Bromelain each play a unique role, but together, they provide comprehensive support for joint health. This synergistic approach is optimal for maintaining flexibility, reducing pain, and supporting the body's natural repair processes.

UNDERSTANDING THE INDIVIDUAL VARIATION IN RESPONSE

It's important to note that individual responses to supplements like FLEXIBLE can vary. Factors such as age, baseline health, lifestyle, and genetic predispositions play a role in how one might benefit from this supplement. Some may experience significant and fast improvements in joint health and flexibility, while others may notice more subtle changes or need more time.

A HOLISTIC APPROACH TO JOINT HEALTH

While FLEXIBLE is an excellent tool in the quest for better joint health, it is most effective when paired with other health-promoting practices:

• Balanced Nutrition: A diet rich in vitamins, minerals, and antioxidants supports overall health and aids the body's natural repair processes [12].
• Regular Exercise: Physical activity keeps joints flexible and strengthens the muscles supporting them [12].
• Adequate Hydration: Staying hydrated is essential for maintaining the health of joint tissue.
• Mindful Lifestyle Choices: Avoiding excessive strain and adopting postures that reduce joint stress can significantly improve joint health.
• Quality Sleep: Adequate and restful sleep is vital for joint health. It allows the body to repair itself, reduces inflammation, and is crucial for overall well-being. Poor sleep can exacerbate joint pain and hinder the body's healing processes [1].

INCORPORATING FLEXIBLE INTO YOUR ROUTINE

Integrating FLEXIBLE into your daily routine is straightforward. Consistent use, as part of a balanced lifestyle, can yield noticeable improvements in joint flexibility and comfort. However, if you have pre-existing health conditions or are taking other medications, it's always recommended to consult with healthcare professionals before starting any new supplement

CONLUSION

In conclusion, FLEXIBLE offers a scientifically-backed comprehensive approach to enhancing joint health and flexibility. Its blend of quality bioactive collagen peptides, glucosamine, MSM, and bromelain contribute uniquely to joint support. Remember, the journey to healthier joints is a holistic one, involving not just supplements but also proper nutrition, regular exercise, and mindful lifestyle choices. With FLEXIBLE as a part of your regimen, you're taking a significant step towards maintaining a youthful, functional, and healthy physique.

REFERENCES

[1] Andersen, M. L., Araujo, P., Frange, C. and Tufik, S. (2018). Sleep disturbance and pain: a tale of two common problems. Chest, 154(5), pp. 1249-1259.

[2] Butawan, M.; Benjamin, R.L.; Bloomer, R.J. (2017). Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients, 9, 290. https://doi.org/10.3390/nu9030290

[3] Daneault, A., Coxam, V. and Wittrant, Y. (2015). Biological Effect of Hydrolyzed Collagen on Bone Metabolism. Critical Reviews in Food Science and Nutrition, 00–00. doi:10.1080/10408398.2015.1038377
10.1080/10408398.2015.1038377

[4] Hewlings, S. and Kalman, D. (2019). Sulfur in human health. EC Nutrition, 14(9), pp. 785-791.

[5] Holwerda, A. M. and van Loon, L. J. (2022). The impact of collagen protein ingestion on musculoskeletal connective tissue remodeling: a narrative review. Nutrition reviews, 80(6), pp. 1497-1514.

[6] Karvat, A. and Bagla, H. Correlation Studies on the Amount of Sulphur in Arthritic Joint Effusion and its Association with Modern and Traditional Medicinal System. (2012). International Journal of Drug Discovery and Herbal Research, 2(3), pp. 446-455.

[7] Kwatra, B. (2019). A review on potential properties and therapeutic applications of bromelain. World J. Pharm. Pharm. Sci, 8(11), pp. 488-500.

[8] Liu, J., Zhang, B., Song, S., Ma, M., Si, S., Wang, Y., . . . Guo, Y. (2014). Bovine collagen peptides compounds promote the proliferation and differentiation of MC3T3-E1 pre-osteoblasts. PLoS One, 9(6), e99920. doi: doi:10.1371/journal.pone.0099920

[9] Martínez-Puig, D.; Costa-Larrión, E.; Rubio-Rodríguez, N.; Gálvez-Martín, P. (2023). Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge. Nutrients, 15, 1332. https://doi.org/10.3390/nu15061332

[10] Nakamura, H. (2011). Application of glucosamine on human disease—Osteoarthritis. Carbohydrate Polymers, 84(2), pp. 835-839.

[11] Persiani Set al. (2007). "Synovial and plasma glucosamine concentrations in osteoarthritic patients following oral crystalline gluçosamine sulphate at therapeutic dose." Osteoarthritis Cartilage, 15, pp.764-772. DOI: 10.1016/j.joca.2007.01.019.

[12] Thomas, S., Browne, H., Mobasheri, A. and Rayman, M. P. (2018). What is the evidence for a role for diet and nutrition in osteoarthritis?. Rheumatology, 57(suppl_4), iv61-iv74.

[13] Varghese, S., Theprungsirikul, P., Sahani, S., Hwang, N., Yarema, K. J. and Elisseeff, J. H. (2007). Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression. Osteoarthritis and Cartilage, 15(1), pp. 59-68.